Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or review is important for guaranteeing the purity and security of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound inside the synthesis of imatinib, a drug that targets particular types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers like breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the generation process and guaranteeing large purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked 17-Diol 17-Acetate to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers including ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have different programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for form two diabetic issues 4-chloro-7-Methoxyquinoline-6-carboxaMide that inhibits the enzyme DPP-4 to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, that are Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication utilised to manage variety two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).